Assay Detail
Functional
CHEMBL4431594
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Dengue virus 1 infected in human PBMC assessed as reduction in viral titer after 48 hrs preincubated with cells prior to ADE-mediated viral infection by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The Medicinal Chemistry of Dengue Virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.10 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7301 | FENRETINIDE | 3.0 | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7301 | FENRETINIDE | EC50 | = | 800.0 | nM | 6.10 |