Assay Detail
Binding
CHEMBL4433342
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Binding affinity to human Cyclic GMP-AMP synthase (2 to 522 residues) expressed in Sf9 cells by surface plasmon resonance analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fragment-to-Lead Medicinal Chemistry Publications in 2017.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.24 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4096573 | — | — | 1 | 6.70 |
| CHEMBL4065757 | — | — | 1 | 3.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4096573 | — | Kd | = | 200.0 | nM | 6.70 |
| CHEMBL4065757 | — | Kd | = | 170000.0 | nM | 3.77 |