Assay Detail
Binding
CHEMBL4434550
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human His-6-tagged PTP4A2 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 as substrate by IMAP-FP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein tyrosine phosphatase type IVA 2 (CHEMBL1075105) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.55 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3393171 | — | — | 1 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3393171 | — | IC50 | = | 280.0 | nM | 6.55 |