Assay Detail
Binding
CHEMBL4480650
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PHD3 (unknown origin) using H1F1-alpha CODD as substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.01 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4482885 | — | — | 1 | 6.66 |
| CHEMBL2042999 | — | — | 1 | 5.98 |
| CHEMBL2043005 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4482885 | — | IC50 | = | 219.0 | nM | 6.66 |
| CHEMBL2042999 | — | IC50 | = | 1050.0 | nM | 5.98 |
| CHEMBL2043005 | — | IC50 | = | 3950.0 | nM | 5.40 |