Assay Detail
Binding
CHEMBL4480652
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Inhibition of KDM4A (unknown origin) using H3 K9Me3 (1 to 15 residues) as substrate
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.12 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2043005 | — | — | 1 | 5.33 |
| CHEMBL4536280 | — | — | 1 | 4.91 |
| CHEMBL4561626 | — | — | 1 | - |
| CHEMBL4573683 | — | — | 1 | - |
| CHEMBL4579945 | — | — | 1 | - |
| CHEMBL4557378 | — | — | 1 | - |
| CHEMBL4514222 | — | — | 1 | - |
| CHEMBL2042999 | — | — | 1 | - |
| CHEMBL4482885 | — | — | 1 | - |
| CHEMBL4535543 | — | — | 1 | - |
| CHEMBL4526672 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2043005 | — | IC50 | = | 4690.0 | nM | 5.33 |
| CHEMBL4536280 | — | IC50 | = | 12350.0 | nM | 4.91 |
| CHEMBL4561626 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4573683 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4579945 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4557378 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4514222 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL2042999 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4482885 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4535543 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4526672 | — | IC50 | > | 25000.0 | nM | - |