Assay Detail
Binding
CHEMBL4482496
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Partial agonist activity at C5a2 receptor (unknown origin) expressed in HEK293 cells assessed as induction of beta-arrestin-2 recruitment incubated for 1 hr by BRET assay
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
C5a anaphylatoxin chemotactic receptor 2 (CHEMBL4523478) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of the first selective c5a2 receptor (c5l2/c5ar2) ligands
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.18 | 5.23 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4518532 | — | — | 2 | 5.23 |
| CHEMBL4550325 | — | — | 2 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4518532 | — | EC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL4550325 | — | EC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL4518532 | — | Activity | - | — | - | |
| CHEMBL4550325 | — | Activity | - | — | - |