Assay Detail
ADMET
CHEMBL4604483
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Cytotoxicity against HEK293 cells incubated for 72 hrs by resazurin dye based assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Orthoscuticellines A-E, β-Carboline Alkaloids from the Bryozoan <i>Orthoscuticella ventricosa</i> Collected in Australia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.00 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4647787 | — | — | 1 | 5.00 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
| CHEMBL441986 | — | — | 1 | - |
| CHEMBL4648910 | — | — | 1 | - |
| CHEMBL4649836 | — | — | 1 | - |
| CHEMBL4640329 | — | — | 1 | - |
| CHEMBL4639278 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4647787 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL76 | CHLOROQUINE | IC50 | > | 40000.0 | nM | - |
| CHEMBL441986 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL4648910 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL4649836 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL4640329 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL4639278 | — | IC50 | > | 40000.0 | nM | - |