Assay Detail
ADMET
CHEMBL4604855
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Cytotoxicity against HEK293 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A Meroisoprenoid, Heptenolides, and <i>C</i>-Benzylated Flavonoids from <i>Sphaerocoryne gracilis</i> ssp. <i>gracilis</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.63 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL469912 | PUROMYCIN | 2.0 | 1 | 6.44 |
| CHEMBL35228 | PYRONARIDINE | 3.0 | 1 | 5.75 |
| CHEMBL36 | PYRIMETHAMINE | 4.0 | 1 | 5.38 |
| CHEMBL4633269 | — | — | 1 | 4.93 |
| CHEMBL4636833 | — | — | 1 | - |
| CHEMBL4647824 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL469912 | PUROMYCIN | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL35228 | PYRONARIDINE | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL36 | PYRIMETHAMINE | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL4633269 | — | IC50 | = | 11800.0 | nM | 4.93 |
| CHEMBL4636833 | — | IC50 | - | — | - | |
| CHEMBL4647824 | — | IC50 | - | — | - |