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Assay Detail

CHEMBL4610467

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat NAAA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

N-acylethanolamine-hydrolyzing acid amidase (CHEMBL2034805)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.
Malamas MS, Farah SI, Lamani M, Pelekoudas DN, Perry NT, Rajarshi G, Miyabe CY, Chandrashekhar H, West J, Pavlopoulos S, Makriyannis A.
Bioorg Med Chem (2020) 28 : 115195 -115195
PubMed 31761726 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.05 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4215669 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4215669 IC50 = 9.0 nM 8.05