Use UniProt Q5KTC7 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2034805 Target Snapshot
N-acylethanolamine-hydrolyzing acid amidase · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q5KTC7. Use UniProt Q5KTC7 as the stable identity anchor, then attach disease evidence before program review.
N-acylethanolamine-hydrolyzing acid amidase
Review this target as N-acylethanolamine-hydrolyzing acid amidase, mapped to UniProt Q5KTC7. Sequence length is 362 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats N-acylethanolamine-hydrolyzing acid amidase as ChEMBL target CHEMBL2034805, mapped to UniProt Q5KTC7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | N-acylethanolamine-hydrolyzing acid amidase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q5KTC7 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | N-acylethanolamine-hydrolyzing acid amidase |
| UniProt Accession | Q5KTC7 |
| Component Type | Protein |
| Sequence Length | 362 aa |
N-acylethanolamine-hydrolyzing acid amidase
How to read this target
Review this target as N-acylethanolamine-hydrolyzing acid amidase, mapped to UniProt Q5KTC7. Sequence length is 362 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3354144 | 8.18 | IC50 | 6.607 | Preclinical |
| CHEMBL2419814 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL4215669 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL3354145 | 7.96 | IC50 | 10.96 | Preclinical |
| CHEMBL2419830 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL3354153 | 7.89 | IC50 | 12.88 | Preclinical |
| CHEMBL3770726 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL3354150 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL3353551 | 7.81 | IC50 | 15.49 | Preclinical |
| CHEMBL2419811 | 7.8 | IC50 | 16.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 32 assays, 165 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 20 | 90 | 5.8 |
| single protein format | 12 | 75 | 6.7 |
ADME — 4 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 0 | — |