Assay Detail
Binding
CHEMBL4610705
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Binding affinity to LPA1 receptor (unknown origin) by cell-based backscattering interferometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA<sub>1</sub>), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.98 | 8.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117021 | LYSOPHOSPHATIDIC ACID | — | 1 | 8.25 |
| CHEMBL4646737 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117021 | LYSOPHOSPHATIDIC ACID | Kd | = | 5.6 | nM | 8.25 |
| CHEMBL4646737 | — | Kd | = | 19.9 | nM | 7.70 |