Assay Detail
Binding
CHEMBL4611100
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reversible binding affinity to full length human N-terminal His6-tagged PDIA1 alpha domain (18 to 134 residues) expressed in Escherichia coli BL21 Gold (DE3) by isothermal titration calorimetry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and evaluation of protein disulfide isomerase inhibitors with nitric oxide releasing activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.21 | 7.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4637290 | — | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4637290 | — | Kd | = | 62.0 | nM | 7.21 |