Assay Detail
Binding
CHEMBL4611693
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Inhibition of Sodium/potassium-transporting ATPase in porcine cerebral cortex using ATP as substrate incubated for 15 mins by ADP-Glo Max Assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.85 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL254219 | DIGITOXIN | 4.0 | 1 | 6.90 |
| CHEMBL449686 | STREBLOSIDE | — | 1 | 6.80 |
| CHEMBL4647504 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL254219 | DIGITOXIN | IC50 | = | 126.8 | nM | 6.90 |
| CHEMBL449686 | STREBLOSIDE | IC50 | = | 159.7 | nM | 6.80 |
| CHEMBL4647504 | — | IC50 | = | 231900.0 | nM | - |