Assay Detail
Binding
CHEMBL4612017
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human NAAA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
N-acylethanolamine-hydrolyzing acid amidase (CHEMBL4349) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
<i>N</i>-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.51 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3770726 | — | — | 1 | 8.22 |
| CHEMBL4643312 | — | — | 1 | 7.64 |
| CHEMBL4218684 | — | — | 1 | 7.52 |
| CHEMBL4641320 | — | — | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3770726 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL4643312 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL4218684 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4641320 | — | IC50 | = | 230.0 | nM | 6.64 |