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Assay Detail

CHEMBL4613341

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of KDM5B (1 to 755 residues) (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lysine-specific demethylase 5B (CHEMBL3774295)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Lysine demethylase 5B (KDM5B): A potential anti-cancer drug target.
Zheng YC, Chang J, Wang LC, Ren HM, Pang JR, Liu HM.
Eur J Med Chem (2019) 161 : 131 -140
PubMed 30343192 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1982368 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1982368 IC50 = 5000.0 nM 5.30