Assay Detail
Binding
CHEMBL4613347
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Antagonist activity against PDL1 (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Peptide-based and small synthetic molecule inhibitors on PD-1/PD-L1 pathway: A new choice for immunotherapy?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.44 | 4.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL366760 | — | — | 1 | 4.44 |
| CHEMBL4639107 | — | — | 1 | - |
| CHEMBL4636289 | — | — | 1 | - |
| CHEMBL4636342 | — | — | 1 | - |
| CHEMBL4637826 | — | — | 1 | - |
| CHEMBL4633569 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL366760 | — | IC50 | = | 36560.0 | nM | 4.44 |
| CHEMBL4639107 | — | IC50 | < | 100.0 | nM | - |
| CHEMBL4636289 | — | IC50 | < | 100.0 | nM | - |
| CHEMBL4636342 | — | IC50 | < | 100.0 | nM | - |
| CHEMBL4637826 | — | IC50 | < | 100.0 | nM | - |
| CHEMBL4633569 | — | IC50 | < | 100.0 | nM | - |