Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4613385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human CDK9/cyclin T after 30 mins in presence of [gamma-33P]ATP by scintillation counter analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

CDK9/cyclin T1 (CHEMBL2111389)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures.
Cheng W, Yang Z, Wang S, Li Y, Wei H, Tian X, Kan Q.
Eur J Med Chem (2019) 164 : 615 -639
PubMed 30639897 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.37 7.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL482193 1 7.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL482193 IC50 = 43.0 nM 7.37