Assay Detail
Functional
CHEMBL4613565
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Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quinolone hybrids and their anti-cancer activities: An overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.75 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4645895 | — | — | 1 | 8.00 |
| CHEMBL481 | IRINOTECAN | 4.0 | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4645895 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL481 | IRINOTECAN | IC50 | = | 32.0 | nM | 7.50 |