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Assay Detail

CHEMBL4613752

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HL60 cells assessed as reduction in cell viability
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Aurone: A biologically attractive scaffold as anticancer agent.
Alsayari A, Muhsinah AB, Hassan MZ, Ahsan MJ, Alshehri JA, Begum N.
Eur J Med Chem (2019) 166 : 417 -431
PubMed 30739824 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.30 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL326574 1 5.52
CHEMBL115120 1 5.37
CHEMBL117137 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL326574 IC50 = 3050.0 nM 5.52
CHEMBL115120 IC50 = 4310.0 nM 5.37
CHEMBL117137 IC50 = 9600.0 nM 5.02