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Assay Detail

CHEMBL4615093

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against mouse NIH/3T3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Autocuration

Target

NIH3T3 (CHEMBL614822)
Type CELL-LINE
Organism Mus musculus

Publication

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease.
Kim M, Hwang I, Pagire HS, Pagire SH, Choi W, Choi WG, Yoon J, Lee WM, Song JS, Yoo EK, Lee SM, Kim MJ, Bae MA, Kim D, Lee H, Lee EY, Jeon JH, Lee IK, Kim H, Ahn JH.
J Med Chem (2020) 63 : 4171 -4182
PubMed 32285676 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.74 4.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4638345 1 4.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4638345 IC50 = 18200.0 nM 4.74