Assay Detail
Binding
CHEMBL4615384
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Binding affinity to BRD9 (unknown origin)
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 8.20 | 9.10 |
| pDC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3823478 | — | — | 1 | 9.10 |
| CHEMBL3769507 | — | — | 1 | 8.70 |
| CHEMBL4635496 | — | — | 1 | 8.70 |
| CHEMBL3823101 | — | — | 1 | 8.20 |
| CHEMBL4065619 | — | — | 1 | 7.50 |
| CHEMBL3753082 | — | — | 1 | 7.00 |
| CHEMBL4643109 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3823478 | — | Kd | = | 0.7943 | nM | 9.10 |
| CHEMBL3769507 | — | Kd | = | 1.995 | nM | 8.70 |
| CHEMBL4635496 | — | Kd | = | 1.995 | nM | 8.70 |
| CHEMBL3823101 | — | Kd | = | 6.31 | nM | 8.20 |
| CHEMBL4065619 | — | Kd | = | 31.62 | nM | 7.50 |
| CHEMBL3753082 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL4643109 | — | pDC50 | = | 7.0 | — | - |