Assay Detail
Binding
CHEMBL4615435
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Inhibition of mouse MAGL
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of Aryl Formyl Piperidine Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.11 | 9.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1232635 | — | — | 1 | 9.66 |
| CHEMBL3087181 | — | — | 1 | 9.56 |
| CHEMBL576786 | — | — | 1 | 8.10 |
| CHEMBL4203881 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1232635 | — | IC50 | = | 0.219 | nM | 9.66 |
| CHEMBL3087181 | — | IC50 | = | 0.275 | nM | 9.56 |
| CHEMBL576786 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4203881 | — | IC50 | < | 100.0 | nM | - |