Assay Detail
Binding
CHEMBL4615736
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDAC6 in mouse N2A cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | N2a |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.90 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2018302 | TUBASTATIN A | — | 1 | 8.36 |
| CHEMBL4636622 | — | — | 1 | 8.01 |
| CHEMBL3970950 | — | — | 1 | 7.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2018302 | TUBASTATIN A | IC50 | = | 4.4 | nM | 8.36 |
| CHEMBL4636622 | — | IC50 | = | 9.7 | nM | 8.01 |
| CHEMBL3970950 | — | IC50 | = | 45.5 | nM | 7.34 |