Assay Detail
Functional
CHEMBL4618166
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Immunosuppressive activity in BALB/c mouse T cells assessed as reduction in ConA-induced cell proliferation
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | T-cell |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Resorcylic Acid Lactones from an <i>Ilyonectria</i> sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 6.04 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL160 | CYCLOSPORINE | 4.0 | 1 | 7.00 |
| CHEMBL4634373 | — | — | 1 | 5.72 |
| CHEMBL4635650 | — | — | 1 | 5.39 |
| CHEMBL4645360 | — | — | 1 | - |
| CHEMBL4637368 | — | — | 1 | - |
| CHEMBL4637614 | — | — | 1 | - |
| CHEMBL1456 | MYCOPHENOLATE MOFETIL | 4.0 | 1 | - |
| CHEMBL4634948 | — | — | 1 | - |
| CHEMBL4648052 | — | — | 1 | - |
| CHEMBL4636152 | — | — | 1 | - |
| CHEMBL4644484 | — | — | 1 | - |
| CHEMBL4640463 | — | — | 1 | - |
| CHEMBL4636544 | — | — | 1 | - |
| CHEMBL4634720 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL160 | CYCLOSPORINE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4634373 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL4635650 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL4645360 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4637368 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4637614 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1456 | MYCOPHENOLATE MOFETIL | IC50 | - | — | - | |
| CHEMBL4634948 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4648052 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4636152 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4644484 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4640463 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4636544 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL4634720 | — | IC50 | > | 25000.0 | nM | - |