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Assay Detail

CHEMBL4621020

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ADMET
Hemolytic activity in human red blood cells after 1 hr
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type Erythrocyte
Confidence 1 — Organism
Curated By Autocuration

Target

Erythrocyte (CHEMBL4296518)
Type CELL-LINE

Publication

Exploring the Sequence Diversity of Cyclotides from Vietnamese Viola Species.
Dang TT, Chan LY, Huang YH, Nguyen LTT, Kaas Q, Huynh T, Craik DJ.
J Nat Prod (2020) 83 : 1817 -1828
PubMed 32437150 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.90 4.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4634725 1 4.96
CHEMBL1801036 CYCLOVIOLACIN O13 1 4.83
CHEMBL4285275 1 -
CHEMBL4646470 1 -
CHEMBL1801140 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4634725 IC50 = 11100.0 nM 4.96
CHEMBL1801036 CYCLOVIOLACIN O13 IC50 = 14900.0 nM 4.83
CHEMBL4285275 IC50 - -
CHEMBL4646470 IC50 - -
CHEMBL1801140 IC50 >= 50000.0 nM -