Assay Detail
Functional
CHEMBL4621695
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Middle East respiratory syndrome coronavirus infected in primary HAE cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Middle East respiratory syndrome-related coronavirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Middle East respiratory syndrome-related coronavirus (CHEMBL4296578) ↗| Type | ORGANISM |
| Organism | Middle East respiratory syndrome-related coronavirus |
Publication
Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.60 | 7.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065616 | REMDESIVIR | 4.0 | 1 | 7.13 |
| CHEMBL2016761 | RDV-TP | -1.0 | 1 | 6.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065616 | REMDESIVIR | EC50 | = | 74.0 | nM | 7.13 |
| CHEMBL2016761 | RDV-TP | EC50 | = | 860.0 | nM | 6.07 |