Assay Detail
Functional
CHEMBL4624409
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Antiproliferative activity against human CNE2Z cells assessed as cell growth inhibition by MTT assay
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CNE2Z |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enzymatic biosynthesis and biological evaluation of novel 17-AAG glucoside as potential anti-cancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.54 | 6.51 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278315 | GELDANAMYCIN | 2.0 | 1 | 6.51 |
| CHEMBL109480 | TANESPIMYCIN | 3.0 | 1 | 5.08 |
| CHEMBL4649689 | — | — | 3 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278315 | GELDANAMYCIN | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL109480 | TANESPIMYCIN | IC50 | = | 8410.0 | nM | 5.08 |
| CHEMBL4649689 | — | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL4649689 | — | Activity | - | — | - | |
| CHEMBL4649689 | — | Activity | - | — | - |