Assay Detail
Functional
CHEMBL4624412
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enzymatic biosynthesis and biological evaluation of novel 17-AAG glucoside as potential anti-cancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.50 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278315 | GELDANAMYCIN | 2.0 | 1 | 6.21 |
| CHEMBL109480 | TANESPIMYCIN | 3.0 | 1 | 5.75 |
| CHEMBL4649689 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278315 | GELDANAMYCIN | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL109480 | TANESPIMYCIN | IC50 | = | 1790.0 | nM | 5.75 |
| CHEMBL4649689 | — | IC50 | = | 28520.0 | nM | 4.54 |