Assay Detail
Binding
CHEMBL4625063
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human wild type partial length HER3 (684 to 987 residues) expressed in mammalian expression system by competitive binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Receptor tyrosine-protein kinase erbB-3 (CHEMBL5838) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potent dual EGFR/Her4 tyrosine kinase inhibitors containing novel (1,2-dithiolan-4-yl)acetamides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.42 | 6.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4646030 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4646030 | — | Kd | = | 380.0 | nM | 6.42 |