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Assay Detail

CHEMBL4625399

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Competitive inhibition of LMW-PTP isoform A (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms.
DeSouza SR, Olson MC, Tinucci SL, Sinner EK, Flynn RS, Marshall QF, Jakubowski HV, McIntee EJ.
Bioorg Med Chem Lett (2020) 30 : 127342 -127342
PubMed 32631543 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.89 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL82202 PYRIDOXAL PHOSPHATE ANHYDROUS 3.0 1 4.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL82202 PYRIDOXAL PHOSPHATE ANHYDROUS Ki = 13000.0 nM 4.89