Assay Detail
Binding
CHEMBL4629192
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus measured after 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Hippocampus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical puzzles in the search for new, flexible derivatives of lurasidone as antipsychotic drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.17 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1237021 | LURASIDONE | 4.0 | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1237021 | LURASIDONE | Ki | = | 6.75 | nM | 8.17 |