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Assay Detail

CHEMBL4649948

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Functional
Phenotypic growth assay for Mycobacterium tuberculosis grown for 4 days on DPPC, cholesterol, tyloxapol based media
ChEMBL ↗
96022
Total Activities
86590
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mycobacterium tuberculosis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545) ↗
Type UNCHECKED

Publication

University of Dundee, Small-Polar-MMV Screening Library
University of Dundee
(2021)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Percent Effect 93556 - -
IC50 2466 4.63 6.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3455348 — — 2 6.74
CHEMBL3437665 — — 2 6.51
CHEMBL3457035 — — 2 6.13
CHEMBL3459598 — — 2 6.10
CHEMBL3448847 — — 2 6.07
CHEMBL3455316 — — 2 6.00
CHEMBL3441718 — — 2 5.98
CHEMBL4534700 — — 2 5.94
CHEMBL3462070 — — 2 5.89
CHEMBL3499578 — — 3 5.80
CHEMBL3445007 — — 2 5.79
CHEMBL3495295 — — 2 5.77
CHEMBL3497732 — — 3 5.70
CHEMBL3453326 — — 2 5.69
CHEMBL3475020 — — 2 5.66
CHEMBL3437497 — — 2 5.64
CHEMBL3468657 — — 2 5.61
CHEMBL3455389 — — 2 5.48
CHEMBL3448179 — — 2 5.46
CHEMBL3483736 — — 2 5.39
CHEMBL3497882 — — 2 5.39
CHEMBL3483168 — — 2 5.39
CHEMBL3436587 — — 2 5.38
CHEMBL3456601 — — 2 5.37
CHEMBL3500915 — — 2 5.37
CHEMBL4530084 — — 2 5.37
CHEMBL3496660 — — 2 5.34
CHEMBL3466452 — — 2 5.33
CHEMBL3463135 — — 2 5.33
CHEMBL3452338 — — 2 5.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3455348 — IC50 = 182.99 nM 6.74
CHEMBL3437665 — IC50 = 307.63 nM 6.51
CHEMBL3457035 — IC50 = 742.49 nM 6.13
CHEMBL3459598 — IC50 = 791.16 nM 6.10
CHEMBL3448847 — IC50 = 854.6 nM 6.07
CHEMBL3455316 — IC50 = 993.93 nM 6.00
CHEMBL3441718 — IC50 = 1053.62 nM 5.98
CHEMBL4534700 — IC50 = 1158.35 nM 5.94
CHEMBL3462070 — IC50 = 1274.32 nM 5.89
CHEMBL3499578 — IC50 = 1594.68 nM 5.80
CHEMBL3445007 — IC50 = 1632.86 nM 5.79
CHEMBL3495295 — IC50 = 1688.32 nM 5.77
CHEMBL3497732 — IC50 = 2019.69 nM 5.70
CHEMBL3453326 — IC50 = 2041.68 nM 5.69
CHEMBL3475020 — IC50 = 2213.66 nM 5.66
CHEMBL3437497 — IC50 = 2313.01 nM 5.64
CHEMBL3468657 — IC50 = 2440.91 nM 5.61
CHEMBL3455389 — IC50 = 3320.81 nM 5.48
CHEMBL3448179 — IC50 = 3445.54 nM 5.46
CHEMBL3483168 — IC50 = 4112.19 nM 5.39
CHEMBL3483736 — IC50 = 4113.89 nM 5.39
CHEMBL3497882 — IC50 = 4050.09 nM 5.39
CHEMBL3436587 — IC50 = 4137.16 nM 5.38
CHEMBL4530084 — IC50 = 4241.59 nM 5.37
CHEMBL3456601 — IC50 = 4300.88 nM 5.37
CHEMBL3500915 — IC50 = 4229.87 nM 5.37
CHEMBL3496660 — IC50 = 4587.36 nM 5.34
CHEMBL3463135 — IC50 = 4625.51 nM 5.33
CHEMBL3466452 — IC50 = 4624.48 nM 5.33
CHEMBL3452338 — IC50 = 4900.42 nM 5.31
CHEMBL3463028 — IC50 = 4964.2 nM 5.30
CHEMBL3445006 — IC50 = 5265.89 nM 5.28
CHEMBL3443960 — IC50 = 5449.34 nM 5.26
CHEMBL3468238 — IC50 = 5473.5 nM 5.26
CHEMBL3488102 — IC50 = 5531.37 nM 5.26
CHEMBL3491689 — IC50 = 5634.17 nM 5.25
CHEMBL3461407 — IC50 = 5633.17 nM 5.25
CHEMBL1481236 — IC50 = 5844.5 nM 5.23
CHEMBL4515835 — IC50 = 5831.6 nM 5.23
CHEMBL3485414 — IC50 = 5924.96 nM 5.23
CHEMBL4559963 — IC50 = 6031.68 nM 5.22
CHEMBL3451626 — IC50 = 6175.68 nM 5.21
CHEMBL3498233 — IC50 = 6387.72 nM 5.20
CHEMBL3447396 — IC50 = 6433.42 nM 5.19
CHEMBL3457410 — IC50 = 6547.69 nM 5.18
CHEMBL3476544 — IC50 = 6671.64 nM 5.18
CHEMBL3467962 — IC50 = 6677.14 nM 5.17
CHEMBL3467996 — IC50 = 6742.83 nM 5.17
CHEMBL3453263 — IC50 = 6839.45 nM 5.17
CHEMBL1713103 — IC50 = 6968.61 nM 5.16