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Assay Detail

CHEMBL4649949

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Functional
Phenotypic growth assay for Mycobacterium tuberculosis grown for 3 days on 7H9, glucose tyloxapol based media
ChEMBL ↗
103984
Total Activities
86576
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mycobacterium tuberculosis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545) ↗
Type UNCHECKED

Publication

University of Dundee, Small-Polar-MMV Screening Library
University of Dundee
(2021)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Percent Effect 101516 - -
IC50 2468 4.60 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3495295 — — 2 6.70
CHEMBL3463478 — — 2 6.68
CHEMBL3453344 — — 3 6.21
CHEMBL3455348 — — 2 6.15
CHEMBL3466452 — — 2 6.05
CHEMBL3499578 — — 3 6.05
CHEMBL3457035 — — 2 6.03
CHEMBL3443805 — — 2 6.02
CHEMBL3469511 — — 3 5.97
CHEMBL3459598 — — 3 5.97
CHEMBL3483860 — — 3 5.88
CHEMBL3468525 — — 2 5.87
CHEMBL3457341 — — 3 5.86
CHEMBL3442015 — — 3 5.84
CHEMBL3440304 — — 2 5.74
CHEMBL3454791 — — 2 5.73
CHEMBL3436886 — — 3 5.71
CHEMBL3437497 — — 3 5.71
CHEMBL3455316 — — 2 5.70
CHEMBL3452338 — — 3 5.62
CHEMBL3486842 — — 3 5.60
CHEMBL3483168 — — 3 5.59
CHEMBL3478649 — — 3 5.59
CHEMBL3481477 — — 3 5.59
CHEMBL3485901 — — 2 5.58
CHEMBL3475240 — — 2 5.57
CHEMBL4534700 — — 2 5.57
CHEMBL4550856 — — 2 5.57
CHEMBL4558867 — — 2 5.56
CHEMBL3448179 — — 2 5.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3495295 — IC50 = 197.78 nM 6.70
CHEMBL3463478 — IC50 = 210.91 nM 6.68
CHEMBL3453344 — IC50 = 609.22 nM 6.21
CHEMBL3455348 — IC50 = 704.15 nM 6.15
CHEMBL3499578 — IC50 = 892.82 nM 6.05
CHEMBL3466452 — IC50 = 883.75 nM 6.05
CHEMBL3457035 — IC50 = 928.1 nM 6.03
CHEMBL3443805 — IC50 = 957.05 nM 6.02
CHEMBL3459598 — IC50 = 1058.86 nM 5.97
CHEMBL3469511 — IC50 = 1072.79 nM 5.97
CHEMBL3483860 — IC50 = 1332.78 nM 5.88
CHEMBL3468525 — IC50 = 1353.53 nM 5.87
CHEMBL3457341 — IC50 = 1381.69 nM 5.86
CHEMBL3442015 — IC50 = 1431.32 nM 5.84
CHEMBL3440304 — IC50 = 1835.17 nM 5.74
CHEMBL3454791 — IC50 = 1849.52 nM 5.73
CHEMBL3436886 — IC50 = 1939.65 nM 5.71
CHEMBL3437497 — IC50 = 1939.91 nM 5.71
CHEMBL3455316 — IC50 = 2012.2 nM 5.70
CHEMBL3452338 — IC50 = 2398.86 nM 5.62
CHEMBL3486842 — IC50 = 2522.21 nM 5.60
CHEMBL3483168 — IC50 = 2538.68 nM 5.59
CHEMBL3481477 — IC50 = 2583.91 nM 5.59
CHEMBL3478649 — IC50 = 2548.65 nM 5.59
CHEMBL3485901 — IC50 = 2658.5 nM 5.58
CHEMBL3475240 — IC50 = 2694.1 nM 5.57
CHEMBL4534700 — IC50 = 2674.17 nM 5.57
CHEMBL4550856 — IC50 = 2725.09 nM 5.57
CHEMBL4558867 — IC50 = 2734.9 nM 5.56
CHEMBL3448179 — IC50 = 2877.99 nM 5.54
CHEMBL3454808 — IC50 = 2952.1 nM 5.53
CHEMBL3468657 — IC50 = 3040.71 nM 5.52
CHEMBL3451132 — IC50 = 3081.79 nM 5.51
CHEMBL3475020 — IC50 = 3176.73 nM 5.50
CHEMBL3484335 — IC50 = 3390.16 nM 5.47
CHEMBL3464578 — IC50 = 3519.52 nM 5.45
CHEMBL3441718 — IC50 = 3537.28 nM 5.45
CHEMBL4521949 — IC50 = 3609.29 nM 5.44
CHEMBL3463135 — IC50 = 3731.08 nM 5.43
CHEMBL3436587 — IC50 = 3753.01 nM 5.43
CHEMBL3461967 — IC50 = 3947.56 nM 5.40
CHEMBL3439297 — IC50 = 4114.41 nM 5.39
CHEMBL3459864 — IC50 = 4027.24 nM 5.39
CHEMBL3457368 — IC50 = 4399.36 nM 5.36
CHEMBL3440196 — IC50 = 4555.72 nM 5.34
CHEMBL3500915 — IC50 = 4718.37 nM 5.33
CHEMBL3482111 — IC50 = 4844.89 nM 5.32
CHEMBL3453355 — IC50 = 4747.5 nM 5.32
CHEMBL3483736 — IC50 = 4939.98 nM 5.31
CHEMBL3497894 — IC50 = 4893.28 nM 5.31