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Assay Detail

CHEMBL4649973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-Wolbachia Cell-Based Screen
ChEMBL ↗
48835
Total Activities
48555
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Wolbachia pipientis
Confidence 1 — Organism
Curated By Autocuration

Target

Wolbachia pipientis (CHEMBL4649981) ↗
Type ORGANISM
Organism Wolbachia pipientis

Publication

University of Dundee, Small-Polar-MMV Screening Library
University of Dundee
(2021)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Percent Effect 48499 - -
IC50 336 5.52 7.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3480436 — — 3 7.08
CHEMBL3457622 — — 3 6.47
CHEMBL3502891 — — 3 6.47
CHEMBL3452782 — — 3 6.46
CHEMBL3500026 — — 3 6.33
CHEMBL3499888 — — 3 6.28
CHEMBL3478581 — — 3 6.25
CHEMBL3481537 — — 3 6.25
CHEMBL3499995 — — 3 6.17
CHEMBL3454186 — — 2 6.16
CHEMBL3493544 — — 3 6.16
CHEMBL3480995 — — 3 6.13
CHEMBL3467616 — — 3 6.08
CHEMBL3473741 — — 3 6.07
CHEMBL3446655 — — 2 5.96
CHEMBL3446025 — — 3 5.96
CHEMBL3469859 — — 2 5.91
CHEMBL3468435 — — 3 5.91
CHEMBL3454277 — — 3 5.88
CHEMBL3446864 — — 2 5.86
CHEMBL3493722 — — 3 5.86
CHEMBL3474685 — — 3 5.85
CHEMBL3482273 — — 3 5.82
CHEMBL3485598 — — 3 5.81
CHEMBL3499986 — — 3 5.81
CHEMBL3462706 — — 3 5.72
CHEMBL3482375 — — 3 5.72
CHEMBL3471683 — — 2 5.72
CHEMBL3472788 — — 2 5.70
CHEMBL3476478 — — 3 5.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3480436 — IC50 = 84.08 nM 7.08
CHEMBL3480436 — IC50 = 155.61 nM 6.81
CHEMBL3457622 — IC50 = 339.79 nM 6.47
CHEMBL3502891 — IC50 = 336.68 nM 6.47
CHEMBL3452782 — IC50 = 348.71 nM 6.46
CHEMBL3502891 — IC50 = 403.51 nM 6.39
CHEMBL3500026 — IC50 = 462.38 nM 6.33
CHEMBL3499888 — IC50 = 526.16 nM 6.28
CHEMBL3478581 — IC50 = 562.42 nM 6.25
CHEMBL3481537 — IC50 = 556.09 nM 6.25
CHEMBL3500026 — IC50 = 594.22 nM 6.23
CHEMBL3499995 — IC50 = 677.88 nM 6.17
CHEMBL3454186 — IC50 = 698.19 nM 6.16
CHEMBL3452782 — IC50 = 699.72 nM 6.16
CHEMBL3481537 — IC50 = 698.19 nM 6.16
CHEMBL3493544 — IC50 = 699.72 nM 6.16
CHEMBL3480995 — IC50 = 745.6 nM 6.13
CHEMBL3467616 — IC50 = 832.57 nM 6.08
CHEMBL3473741 — IC50 = 851.16 nM 6.07
CHEMBL3499995 — IC50 = 957.66 nM 6.02
CHEMBL3446655 — IC50 = 1085.22 nM 5.96
CHEMBL3446025 — IC50 = 1106.44 nM 5.96
CHEMBL3468435 — IC50 = 1219.09 nM 5.91
CHEMBL3469859 — IC50 = 1218.66 nM 5.91
CHEMBL3473741 — IC50 = 1239.08 nM 5.91
CHEMBL3454277 — IC50 = 1318.96 nM 5.88
CHEMBL3499888 — IC50 = 1340.17 nM 5.87
CHEMBL3454277 — IC50 = 1373.94 nM 5.86
CHEMBL3493722 — IC50 = 1388.77 nM 5.86
CHEMBL3446864 — IC50 = 1393.82 nM 5.86
CHEMBL3474685 — IC50 = 1410.86 nM 5.85
CHEMBL3446025 — IC50 = 1470.38 nM 5.83
CHEMBL3469859 — IC50 = 1470.28 nM 5.83
CHEMBL3482273 — IC50 = 1521.34 nM 5.82
CHEMBL3485598 — IC50 = 1553.25 nM 5.81
CHEMBL3499986 — IC50 = 1536.51 nM 5.81
CHEMBL3499986 — IC50 = 1570.56 nM 5.80
CHEMBL3485598 — IC50 = 1748.08 nM 5.76
CHEMBL3482273 — IC50 = 1815.09 nM 5.74
CHEMBL3446864 — IC50 = 1873.21 nM 5.73
CHEMBL3471683 — IC50 = 1910.64 nM 5.72
CHEMBL3482375 — IC50 = 1917.65 nM 5.72
CHEMBL3462706 — IC50 = 1888.65 nM 5.72
CHEMBL3462706 — IC50 = 1910.64 nM 5.72
CHEMBL3472788 — IC50 = 1977.24 nM 5.70
CHEMBL3474685 — IC50 = 2055.18 nM 5.69
CHEMBL3457622 — IC50 = 2074.19 nM 5.68
CHEMBL3446655 — IC50 = 2096.59 nM 5.68
CHEMBL3476478 — IC50 = 2116.93 nM 5.67
CHEMBL3477115 — IC50 = 2187.47 nM 5.66