Assay Detail
Binding
CHEMBL4650198
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reverse ITC (compound as receptor). Domain start/stop: E348-D455
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | ITC assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
EUbOPEN bromodomain assay panel
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.30 | 7.30 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Protein Sequence | Protein Sequence | - | — | MHHHHHHSSGVDLGTENLYFQSMEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD |
| Refseq Start/Stop | Refseq Start/Stop | - | — | E348-D455 |
| Target UniProt Accession | Target UniProt Accession | - | — | P25440 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3133807 | — | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3133807 | — | Kd | = | 50.3 | nM | 7.30 |