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Assay Detail

CHEMBL4668336

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of androgen receptor AF1 domain (141 to 486 residues) (unknown origin) incubated for 30 mins by steady-state fluorescence emission spectroscopy
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Androgen receptor (CHEMBL1871)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Monomeric Targeted Protein Degraders.
Hanan EJ,Liang J,Wang X,Blake RA,Blaquiere N,Staben ST
J Med Chem (2020) 63 : 11330 -11361
PubMed 32352776 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.89 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4444904 1 5.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4444904 Kd = 1300.0 nM 5.89