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Assay Detail

CHEMBL4668436

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Functional
Cytotoxicity against human HaCaT cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HaCaT
Confidence 1 — Organism
Curated By Autocuration

Target

HaCaT (CHEMBL614392)
Type CELL-LINE
Organism Homo sapiens

Publication

Colchicine Alkaloids and Synthetic Analogues: Current Progress and Perspectives.
Gracheva IA,Shchegravina ES,Schmalz HG,Beletskaya IP,Fedorov AY
J Med Chem (2020) 63 : 10618 -10651
PubMed 32432867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.46 8.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4747139 1 8.46
CHEMBL4765034 1 8.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4747139 IC50 = 3.5 nM 8.46
CHEMBL4765034 IC50 = 3.5 nM 8.46