Assay Detail
Binding
CHEMBL4668508
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at androgen receptor (unknown origin) expressed in human HeLa cells harboring AR3A-PSA-(ARE)4-Luc13 in presence of DHT by BrightGlo luciferase assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Overview of AKR1C3: Inhibitor Achievements and Disease Insights.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.18 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4439327 | — | — | 1 | 5.68 |
| CHEMBL2023820 | — | — | 1 | 4.68 |
| CHEMBL4513510 | ASP-9521 | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4439327 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL2023820 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL4513510 | ASP-9521 | IC50 | = | 300000.0 | nM | - |