Assay Detail
Binding
CHEMBL4668623
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK2/Cyclin A (unknown origin) using histone H1 as substrate by scintillation counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Fragment Linking Strategies for Structure-Based Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL270054 | GW280670X | — | 1 | 7.52 |
| CHEMBL327012 | — | — | 1 | - |
| CHEMBL7204 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL270054 | GW280670X | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL327012 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL7204 | — | IC50 | > | 1000000.0 | nM | - |