Assay Detail
Binding
CHEMBL4668630
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of caspase-3 (unknown origin) using Ac-DEVD-AMCA as substrate incubated for 5 mins by Dixon plot analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fragment Linking Strategies for Structure-Based Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.21 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4751195 | — | — | 1 | 10.10 |
| CHEMBL4782926 | — | — | 1 | 7.60 |
| CHEMBL234378 | — | — | 1 | 3.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4751195 | — | Ki | = | 0.08 | nM | 10.10 |
| CHEMBL4782926 | — | Ki | = | 25.0 | nM | 7.60 |
| CHEMBL234378 | — | Ki | = | 120000.0 | nM | 3.92 |