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Assay Detail

CHEMBL4669579

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Zika virus
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Zika virus
Confidence 1 — Organism
Curated By Autocuration

Target

Zika virus (CHEMBL4296612)
Type ORGANISM
Organism Zika virus

Publication

Diverse Types of Diterpenoids with an Aromatized C Ring from the Twigs of Podocarpus imbricatus.
Zhou B,Ren YH,Han YS,Mesplède T,Yue JM
J Nat Prod (2020) 83 : 2416 -2424
PubMed 32786878 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 3 - -
IC50 2 7.55 9.49

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL866 MYCOPHENOLIC ACID 4.0 1 9.49
CHEMBL4763844 1 5.60
CHEMBL4750754 1 -
CHEMBL4749619 1 -
CHEMBL4752418 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL866 MYCOPHENOLIC ACID IC50 = 0.32 nM 9.49
CHEMBL4763844 IC50 = 2500.0 nM 5.60
CHEMBL4750754 Activity - -
CHEMBL4749619 Activity - -
CHEMBL4752418 Activity - -