Assay Detail
Binding
CHEMBL4670903
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Vgamma9Vdelta2 T cell |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Butyrophilin subfamily 3 member A1 (CHEMBL4105758) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.77 | 10.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145233 | — | — | 1 | 10.22 |
| CHEMBL923 | RISEDRONIC ACID | 4.0 | 1 | 7.10 |
| CHEMBL356362 | ISOPENTENYLPYROPHOSPHATE | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145233 | — | EC50 | = | 0.06 | nM | 10.22 |
| CHEMBL923 | RISEDRONIC ACID | EC50 | = | 80.0 | nM | 7.10 |
| CHEMBL356362 | ISOPENTENYLPYROPHOSPHATE | EC50 | = | 1000.0 | nM | 6.00 |