Assay Detail
ADMET
CHEMBL4673728
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Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 48 hrs by resazurin dye based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.16 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4749932 | — | — | 1 | 5.33 |
| CHEMBL2095053 | — | — | 1 | 4.98 |
| CHEMBL4751801 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4749932 | — | IC50 | = | 4630.0 | nM | 5.33 |
| CHEMBL2095053 | — | IC50 | = | 10400.0 | nM | 4.98 |
| CHEMBL4751801 | — | IC50 | - | — | - |