Assay Detail
ADMET
CHEMBL4673734
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Cytotoxicity against rat L6 cells assessed as reduction in cell viability after 70 hrs by Alamar blue dye-based fluorometric analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.02 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | 4.0 | 1 | 7.96 |
| CHEMBL4741937 | — | — | 1 | 4.60 |
| CHEMBL4785398 | — | — | 1 | 4.60 |
| CHEMBL4786148 | — | — | 1 | 4.52 |
| CHEMBL4751801 | — | — | 1 | 4.26 |
| CHEMBL4761032 | — | — | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL4741937 | — | IC50 | = | 24950.0 | nM | 4.60 |
| CHEMBL4785398 | — | IC50 | = | 25150.0 | nM | 4.60 |
| CHEMBL4786148 | — | IC50 | = | 30400.0 | nM | 4.52 |
| CHEMBL4751801 | — | IC50 | = | 54450.0 | nM | 4.26 |
| CHEMBL4761032 | — | IC50 | = | 65400.0 | nM | 4.18 |