Assay Detail
Functional
CHEMBL4677626
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human JJN-3 cells transfected with plasmid expressing NIK
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | JJN-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.21 | 7.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4741330 | — | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4741330 | — | EC50 | = | 61.0 | nM | 7.21 |