Assay Detail
Binding
CHEMBL4677780
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to SMARCA2 (unknown origin) by ITC analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Probable global transcription activator SNF2L2 (CHEMBL2362979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.16 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4780617 | — | — | 1 | 7.46 |
| CHEMBL4793170 | — | — | 1 | 7.16 |
| CHEMBL4790365 | — | — | 1 | 7.15 |
| CHEMBL4746865 | — | — | 1 | 6.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4780617 | — | Kd | = | 35.0 | nM | 7.46 |
| CHEMBL4793170 | — | Kd | = | 69.0 | nM | 7.16 |
| CHEMBL4790365 | — | Kd | = | 71.0 | nM | 7.15 |
| CHEMBL4746865 | — | Kd | = | 135.0 | nM | 6.87 |