Assay Detail
Binding
CHEMBL4679900
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human HPGDS using [14C]-PGH2 as substrate preincubated for 1 min in presence of MgCl2 followed by substrate addition and measured after 45 mins by radioactive imaging analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Hematopoietic prostaglandin D synthase (CHEMBL5879) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.08 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4238186 | — | — | 1 | 7.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4238186 | — | IC50 | = | 83.0 | nM | 7.08 |