Assay Detail
Functional
CHEMBL4680971
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Antiplasmodial activity against Plasmodium yoelli liver stage forms
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium yoelii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.54 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4091762 | CABAMIQUINE | 2.0 | 1 | 9.00 |
| CHEMBL4764214 | — | — | 1 | 9.00 |
| CHEMBL4783407 | — | — | 1 | 8.40 |
| CHEMBL4781713 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4091762 | CABAMIQUINE | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4764214 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4783407 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL4781713 | — | EC50 | = | 18.0 | nM | 7.75 |