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Assay Detail

CHEMBL4684680

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human SR cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SR
Confidence 1 — Organism
Curated By Autocuration

Target

SR (CHEMBL614300)
Type CELL-LINE
Organism Homo sapiens

Publication

1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226.
Ashour HF,Abou-Zeid LA,El-Sayed MA,Selim KB
Eur J Med Chem (2020) 189 : 112062 -112062
PubMed 31986406 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.02 6.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4778826 1 6.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4778826 IC50 = 960.0 nM 6.02