Assay Detail
Functional
CHEMBL4686967
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Antiviral activity against human Norovirus
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Norovirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.99 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223482 | — | — | 1 | 5.50 |
| CHEMBL438605 | — | — | 1 | 5.09 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223482 | — | EC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL438605 | — | EC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 43000.0 | nM | 4.37 |